Domain Therapeutics
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Domain Therapeutics, a clinical-stage global biopharmaceutical company, focused on developing innovative immunotherapies targeting G Protein-Coupled Receptors (GPCRs), one of the most important drug target classes, to unlock new possibilities in cancer. As a leader in GPCRs in immuno-oncology, Domain sees cancer differently, using a precise biomarker strategy to address the specific needs of patients based on unique signatures of individual cancers. Two decades of solid experience in GPCR drug discovery, validated by multiple pharma partnerships, associated to a target identification and drug discovery platform enable the Company to enhance the understanding of cancer and deliver innovative immunotherapies to patients.
Domain's proprietary programs include DT-7012, a Treg-depleting CCR8 antibody, DT-9045, a first-in-class PAR2 negative allosteric modulator, and DT-9081, an EP4 receptor antagonist alongside the M1069, an A2aR/A2b receptor antagonist identified in partnership with Merck KGaA. The company has also an optimized pipeline of best-in-class and first-in-class GPCR targets selected through Domain's proprietary cross-validation drug discovery and development platform.
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biotechnology, life sciences, gpcr, immunooncology, cancer, immunotherapy, clinical research, drug development, precision research, precision medicine, clinical trials, cancer research, drug discovery, biopharma, innovation, sustainability, cancer treatment, immunosuppression, patientcentered approach, immune system, cancer immunotherapy, tumor biology, tumor microenvironment, immunoresistance, clinical development, cancerfocused gpcr targets, biomarkers, soft mobility, green mobility, sustainable mobility, sustainable transportation, sustainable future, inflammation
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