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The UVRI engages in health research pertaining to human infections and disease processes associated with or linked to viral aetiology and provides expert advice, enables partnerships and communication and serves as a center for training and education.

UVRI conducts research, surveillance and diagnostics. The Institute's programmatic activities currently comprise of the following areas:
-Basic research (e.g virology, immunology, genetics, genomics, molecular biology)
-Applied research (intervention, diagnostics, clinical, operational)
-Social/economic research
-Surveillance
-Epidemiology
-Entomology
-Bioinformatics
-Capacity building through infrastructure and human resource development
-Advice for regulation, policy development and quality improvement
-Innovation.

We are home to several national and international reference and specialized testing laboratories including:

-The national and regional reference center for vector borne viral diseases;
-The national influenza Ccnter, a WHO influenza collaborating laboratory;
-The national diagnostic laboratory for highly infectious viral infections;
-The Africa WHO yellow fever reference laboratory;
-The national HIV reference and quality assurance laboratory;
-The national and regional reference laboratory for HIV drug resistance,
-A WHO Measles and Rubella Regional Reference laboratory and
-WHO Inter-country Polio laboratory.

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